by UanarchyK
The numbers on the cards of the legacy deck always refer to dossier doors. Any boxes you need to open will be explicitly specified.Also, there is a FAQ on here that has common rules clarifications for each month hidden behind a spoiler tag. This a great resource, because you can check the FAQ without worrying about spoiling future months.
Lastly, I would say it is absolutely crucial that you've played Pandemic before playing this. If you haven't, the number of things to keep track of will become very difficult.
other than that, enjoy!