by albcann
There is one character that can form a team with fewer than 5 cards ... that will help.Play the prologue over and over until you feel comfortable with it. Once you figure out the synergies among the character abilities, things will get easier.
Sometimes, the luck of the draw kills you quickly ... accept that, it happens.
You say this is your first legacy game? Surprised you didn't start with Pandemic Legacy Season 1. Yes, it can be played chronologically, but most (and I concur) recommend playing the series in order of release ... 1,2,0. Season 1, IMHO, is an easier game than Season 2 or 0.